drugset / Trial / NCT06724978

A Study of S-740792 in Healthy Adult Study Participants

NCT06724978 ↗

Phase 1 Completed 99 enrolled Shionogi
RandomizedSequentialQuadruple-blindTreatment

Summary

This is a 3-part study of S-740792 in healthy adult participants. Part 1 (single-ascending-dose and food effect) will investigate the safety, tolerability, and pharmacokinetics (PK) of S-740792. Part 2 (multiple-ascending-dose and drug-drug interaction) will investigate the safety, tolerability, and PK of S-740792, in addition, the effect of multiple doses of S-740792 on the PK of midazolam. Part 3 will investigate the relative bioavailability of S-740792 tablet compared to S-740792 suspension and the food effect on the PK of the S-740792 tablet.

Timeline

Start
2024-11-21
Primary completion
2025-09-10
Completion
2025-09-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Midazolam Small molecule — Oral
Subject S-740792 Unknown — Oral

Indications

No indication recorded.