drugset / Trial / NCT06726174
Cell Therapy for Corneal Endothelial Cell Dysfunction
NaSingle-groupOpen-labelTreatment
Summary
Culture endothelial cells harvested from donor corneal tissue to treat corneal endothelial cell dysfunction. After ex vivo cultivation, the cells will be injected into anterior chamber and endothelial cells will settle down and adhere to the denuded Descemet's membrane. Eventually, they will reconstitute functional corneal endothelium to subside the corneal edema and improve the visual acuity.
Timeline
- Start
- 2025-04-25
- Primary completion
- 2028-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ECCEC | Cell therapy | 500000 cells | Other |
| Subject | ECCEC | Cell therapy | 1e+06 cells | Other |