drugset / Trial / NCT06727331

Study of Tirzepatide for Recovery and Alcohol Use Management

NCT06727331

Phase 2 Recruiting 20 enrolled Brigham and Women's Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

This is a pilot, 4-week, double-blind, placebo-controlled, randomized trial of individuals with alcohol use disorder (AUD) to receive weekly injections of either tirzepatide (n=10) or matching placebo (n=10). The primary aim is to determine the effects of tirzepatide on cue-reactivity among individuals with AUD. The secondary aim is to assess the safety and preliminary efficacy of tirzepatide for AUD.

Timeline

Start
2025-09-15
Primary completion
2027-03-01
Completion
2027-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tirzepatide Peptide 2.5 mg