drugset / Trial / NCT06732518
Evaluation of the Anti-cavity Efficacy of Three Dentifrices Using an Intra-oral Enamel Demineralization - Remineralization In-Situ Model
RandomizedCrossoverQuadruple-blindOther
Summary
Clinical study to evaluate the anti-cavity efficacy of three dentifrices using an intra-oral enamel Demineralization - Remineralization In-Situ Model. This is a Phase III, single-center, triple-blind with a crossover design. It involves 36 participants aged between 18 and 70, randomized into 3 different groups + a washout group, and spans 6 weeks.
Timeline
- Start
- 2025-03-13
- Primary completion
- 2025-04-24
- Completion
- 2025-04-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluoride | Other / unclassified | 1.5 % | — |
| Subject | Fluoride | Other / unclassified | 1000 ppm | — |
| Subject | Fluoride free toothpaste in a PCC/RNCC base | Unknown | — | — |
| Comparator | Fluoride free toothpaste in a chalk base | Unknown | — | — |