drugset / Trial / NCT06735235

Salivary Fluoride Clearance

NCT06735235 ↗

Phase 1 Completed 27 enrolled Procter and Gamble
RandomizedCrossoverDouble-blindBasic science

Summary

This is a single-center, four-treatment, four-period crossover study. Over the course of the study, up to thirty qualified subjects will use four (4) study treatment products, one time each according to the randomization. Subjects will brush with 1.25g of the assigned study product at each visit. Subjects will provide saliva samples at baseline and at 2, 6, 12, and 30 minutes post-treatment. The F- concentrations in each saliva sample will be determined by ion chromatography

Timeline

Start
2021-07-14
Primary completion
2021-07-29
Completion
2021-07-29

Drugs

EvaluationDrugModalityDoseRoute
Subject MFP Unknown 250 ppm Topical
Subject MFP Unknown 1100 ppm Topical
Subject MFP Unknown 2800 ppm Topical

Indications