drugset / Trial / NCT06735235
Salivary Fluoride Clearance
RandomizedCrossoverDouble-blindBasic science
Summary
This is a single-center, four-treatment, four-period crossover study. Over the course of the study, up to thirty qualified subjects will use four (4) study treatment products, one time each according to the randomization. Subjects will brush with 1.25g of the assigned study product at each visit. Subjects will provide saliva samples at baseline and at 2, 6, 12, and 30 minutes post-treatment. The F- concentrations in each saliva sample will be determined by ion chromatography
Timeline
- Start
- 2021-07-14
- Primary completion
- 2021-07-29
- Completion
- 2021-07-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MFP | Unknown | 250 ppm | Topical |
| Subject | MFP | Unknown | 1100 ppm | Topical |
| Subject | MFP | Unknown | 2800 ppm | Topical |