drugset
drugset / Trial / NCT06737666

Study on the Effectiveness and Mechanism of Tong-Xie-Yao-Fang in Treating Diarrhea-predominant Irritable Bowel Syndrome

NCT06737666 ↗

Phase 1 Recruiting 60 enrolled Xiyuan Hospital of China Academy of Chinese Medical Sciences
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Traditional Chinese Medicine focuses on the main pathogenesis of liver depression and spleen deficiency, and treats them from the perspective of soothing the liver and strengthening the spleen to treat on Diarrhea-predominant irritable bowel syndrome (IBS-D) . The classic formula for treating is the Tong-Xie-Yao-Fang (TXYF). Based on metabolomics and metagenomics, the research group studied the intestinal flora and host co metabolism of TXYF in the treatment of diarrhea predominant IBS-D, in order to clarify the mechanism of TXYF in the treatment of IBS-D.

Timeline

Start
2023-05-29
Primary completion
2025-10-08
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Tong-Xie-Yao-Fang Traditional medicine (herbal / TCM) 2 unknown —

Indications

irritable bowel syndrome