drugset / Trial / NCT06738407
Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections
Phase 4
Recruiting
760 enrolled
Westat
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collabFlorida State University · collabNational Institute of Allergy and Infectious Diseases (NIAID) · collabNational Institute of Mental Health (NIMH) · collabNational Institute on Drug Abuse (NIDA) · collabThe Office of the Director, National Institutes of Health (NIH) · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
The goal of this open-label, randomized trial is to assess the efficacy of doxycycline prophylaxis in reducing incidences of bacterial sexually transmitted infections (STIs) among adolescent and young adult females while also evaluating acceptability and antimicrobial resistance in order to inform public health policy.
Timeline
- Start
- 2026-02-27
- Primary completion
- 2028-06-15
- Completion
- 2028-06-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 200 mg | Oral |