drugset / Trial / NCT06738966
A Study of BL0175 Injection in Postmenopausal Female Adults With HR-positive, Locally Advanced or Metastatic Cancer
Non-randomizedSequentialOpen-labelTreatment
Summary
The goal of this clinical trial is to learn if the investigational drug BL0175 works to treat adult postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor (HER2)-negative locally advanced or metastatic breast cancer, ovarian cancer and endometrial cancer. It will also learn about the safety of BL0175. The main questions it aims to answer are: * Does the investigational drug BL0175 is safe for participants after dosed -multiple times? * Which is the highest safety dose of BL0175 after multiple dose? * What medical problems do participants have when using BL0175? * Does the investigational drug BL0175 works for participants after dosed -multiple times?
Timeline
- Start
- 2025-03-10
- Primary completion
- 2026-02-20
- Completion
- 2027-12-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BL0175 | Other / unclassified | 50 mg | — |
| Subject | BL0175 | Other / unclassified | 100 mg | — |
| Subject | BL0175 | Other / unclassified | 200 mg | — |
| Subject | BL0175 | Other / unclassified | 400 mg | — |
| Subject | BL0175 | Other / unclassified | 500 mg | — |