Intraoperative 5-fluorouracil Augmentation of Trabeculectomy

Summary

5-fluorouracil (5FU) is an antimetabolite that has been demonstrated to have beneficial effects when injected into the subconjunctival space after glaucoma surgery (trabeculectomy). The hypothesis of this study is that a similar beneficial effect can be achieved with a single intraoperative application of 5FU. This hypothesis is tested with a randomized control study.

Timeline

Start

1996-04

Primary completion

2000-06

Completion

2003-06

Drugs

Indications