drugset / Trial / NCT06750289

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

NCT06750289

Phase 3 Recruiting 400 enrolled AstraZeneca
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study evaluates the efficacy and safety of benralizumab as an add-on therapy in uncontrolled eosinophilic asthma participants treated with medium-dose ICS-LABA compared to the conventional treatment step of escalation of inhaled therapy to high-dose ICS-LABA.

Timeline

Start
2025-03-28
Primary completion
2028-11-03
Completion
2028-11-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Benralizumab Monoclonal antibody 30 mg Subcutaneous

Indications