drugset / Trial / NCT06761027
mFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study is a prospective, single-arm, multicenter, phase Ib/II clinical trial that treats previously untreated patients with locally advanced or metastatic pancreatic cancer using mFOLFIRINOX in combination with anlotinib and sintilimab. The purpose of this trial is to evaluate the efficacy and safety of this treatment regimen and to preliminarily explore the correlation between biomarkers and treatment outcomes.
Timeline
- Start
- 2024-12-23
- Primary completion
- 2027-03
- Completion
- 2027-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Catequentinib | Small molecule | 8 mg | Oral |
| Subject | Catequentinib | Small molecule | 10 mg | Oral |
| Subject | Sintilimab | Monoclonal antibody | — | — |