drugset / Trial / NCT06764056

Characterization and Management of Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)

NCT06764056

RandomizedParallel-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to improve the treatment of hepatic steatosis associated with obesity with pharmacological and nutritionnal approaches. The main question it aims to answer is: Does an individualized nutritionnal approach with a dietician combined with medication targeting obesity is the most efficient way to treat hepatic steatosis associated with obesity? Participants will either participate in one of three groups: * Nutrition: Participant will only have a regular follow-up with a registered dietician; * Nutrition + Semaglutide: Participants will start a new medication targeting obesity and will have a regular follow-up with a registered dietician; * Semaglutide: Participants will start a new medication targeting obesity.

Timeline

Start
2025-01
Primary completion
2026-05
Completion
2026-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Semaglutide Peptide 1 mg
Comparator Semaglutide Peptide 2.4 mg