drugset / Trial / NCT06770842

Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis

NCT06770842

Phase 2 Recruiting 20 enrolled The University of Hong Kong
NaSingle-groupOpen-labelTreatment

Summary

In this open-label single arm phase 2 study, approximately 20 patients with MF demonstrating suboptimal response to ruxolitinib monotherapy will be enrolled. Patients will continue to receive ruxolitinib at a stable dose and ropeginterferon alfa 2b will be added to the regimen.

Timeline

Start
2025-03-01
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ropeginterferon alfa-2b Protein / enzyme biologic 500 ug Subcutaneous