drugset / Trial / NCT06771115

Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in Obesity

NCT06771115

Phase 2 Completed 176 enrolled Zomagen Biosciences Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a study to understand if taking VTX3232 alone or in combination with semaglutide is safe in participants diagnosed with Obesity. Approximately 160 patients will take VTX3232 Dose A, Placebo, VTX3232 Dose A in combination with semaglutide, or Placebo in combination with semaglutide. This study consists of a 30-day Screening Period (to see if a participant qualifies for a study), a 12-week double-blind treatment period (a participant receives VTX3232 Dose A, Placebo, VTX3232 Dose A in combination with semaglutide, or Placebo in combination with semaglutide), and a 30-day Follow-Up Period. The maximum duration of treatment will be approximately 12 weeks.

Timeline

Start
2025-01-07
Primary completion
2025-09-10
Completion
2025-09-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Semaglutide Peptide
Subject VTX3232 Unknown

Indications