drugset

drugset / Trial / NCT06775730

A Drug-Drug Interaction Study of S-217622 With Combined Oral Contraceptives in Healthy Adult Female Participants

NCT06775730 ↗

Phase 1 Completed 24 enrolled Shionogi

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to examine the potential for drug-drug interactions.

Timeline

Start: 2024-12-30
Primary completion: 2025-04-03
Completion: 2025-04-03

Publications

Shimizu R, Shibata RY, Kubota R, Okuda S, Sonoyama T. Effects of Ensitrelvir on the Pharmacokinetics of Combined Oral Contraceptives (Ethinyl Estradiol/Drospirenone) in Healthy Adult Women: A Phase 1 Fixed-Sequence, Multiple-Dose, Drug-Drug Interaction Study. Clin Drug Investig. 2026 May;46(5):561-570. doi: 10.1007/s40261-026-01541-3. Epub 2026 Mar 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ensitrelvir	Small molecule	125 mg	Oral

Indications

No indication recorded.