drugset / Trial / NCT06775964

Stem Cell Therapy for Early Alzheimer's Disease

NCT06775964 ↗

Phase 1/2 Recruiting 12 enrolled Paul E Schulz Weston Brain Institute · collab
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to learn if stem cell therapy works to treat brain inflammation in adults. Inflammation in the brain may be involved in adults who have memory or thinking problems. The stem cells will be taken from participant's fat samples, processed and given back to participants, so they are their own donor. The main questions this trial aims to answer are: * Does stem cell therapy reduce inflammation in the brain? * Does stem cell therapy improve brain activity? * Does stem cell therapy slow down progression to Alzheimer's disease? Participants will: * Have a small fat biopsy taken at a doctor's office to process stem cells * Receive 4 infusions of stem cells, through a vein in the arm over 12 weeks * Visit the clinic every 2-4 weeks for the first 4 months and then every 1-2 months for 8 months for checkups and tests

Timeline

Start
2026-03-11
Primary completion
2027-01
Completion
2028-01

Drugs

EvaluationDrugModalityDoseRoute
Subject AdMSC Cell therapy 2e+08 cells Intravenous

Indications