drugset / Trial / NCT06777173

Clinical Study of Antiviral Therapy Combined With Novel Immunotherapy for CHB in Adults

NCT06777173

Enrolling by invitation 180 enrolled Beijing Ditan Hospital
NaSingle-groupOpen-labelTreatment

Summary

Establish a study cohort of adult chronic hepatitis B antiviral treatment based on the principle of responseguidedtreatment (RGT) corresponding to the child cohort, analyze the clinical cure factors of IC and IT stage adults chronic hepatitis B, and optimize the antiviral treatment plan. To determine the safety and efficacy of PD-1 antibody combined with Peg-FNa-2b in the treatment of adult NAs patients with CHB advantage.

Timeline

Start
2023-12-01
Primary completion
2026-11-01
Completion
2026-11-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Peginterferon alfa-2b Protein / enzyme biologic