drugset / Trial / NCT06777316

A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors

NCT06777316 ↗

Phase 1/2 Active not recruiting 110 enrolled Cogent Biosciences, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetic (what the body does to the drug), pharmacodynamic (what the drug does to the body), and antitumor activity of CGT4859 in adult participants with intrahepatic cholangiocarcinoma (iCCA) or other advanced solid tumors with FGFR2 and/or FGFR3 genetic alternations.

Timeline

Start
2025-01-22
Primary completion
2027-03
Completion
2027-06

Drugs

EvaluationDrugModalityDoseRoute
Subject CGT4859 Unknown — Oral