EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA

Summary

This study aims at assessing the non-inferiority of tested formula facial serum (2039125 03) versus hydroquinone 4% over 3 months for treatment and then 3 months for maintenance ofwomen subjects presenting facial melasma.

Timeline

Start

2023-08-17

Primary completion

2024-03-12

Completion

2024-03-12

Publications

• Passeron T, Kerob D, Le Dantec G, Demessant-Flavigny AL, do Nascimento AR, Moura R, Salah S, Feiges M, Fernandez E, Alexis A. Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma. Dermatol Ther (Heidelb). 2025 Sep;15(9):2379-2390. doi: 10.1007/s13555-025-01473-4. Epub 2025 Jun 30.

Drugs

Indications