drugset / Trial / NCT06789796

a Study of QL1706 or QL1604 in Patients With Limited-stage Small Cell Lung Cancer After Chemoradiotherapy.

NCT06789796

Phase 3 Not yet recruiting 636 enrolled Qilu Pharmaceutical Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study is being conducted to evaluate the efficacy and safety of QL1706 versus QL1604 monotherapy as consolidation treatment in patients with limited-stage small cell lung cancer (LS-SCLC) who have not experienced disease progression after concurrent or sequential chemoradiotherapy. QL1706 (Iparomlimab and Tuvonralimab) is a single bifunctional MabPair product against PD-1 and CTLA-4. QL1604 is a monoclonal antibody against PD-1.

Timeline

Start
2025-02
Primary completion
2028-03
Completion
2030-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator QL1604 Monoclonal antibody 200 mg Intravenous
Subject QL1706 Monoclonal antibody 5 mg/kg Intravenous