A Study of ESO-T01 in Treating Relapsed/ Refractory Multiple Myeloma

Summary

This is a single center, single arm, open-label, dose-escalation clinical study to observe the safety, tolerability, preliminary efficacy, pharmacokinetics, pharmacodynamics of ESO-T01 injection for treating patients with relapsed/refractory multiple myeloma.

Timeline

Start

2025-01-27

Primary completion

2027-11-30

Completion

2027-11-30

Publications

• An N, Wang D, Zhang P, Zhang J, Parone P, Hu J, Bao Y, Xu L, Ruan H, Wan Y, Wen X, Gao Y, Li C. In vivo generation of anti-BCMA CAR-T cells in relapsed or refractory multiple myeloma: a phase 1 study. Nat Med. 2026 Apr;32(4):1257-1266. doi: 10.1038/s41591-026-04244-6. Epub 2026 Mar 25.

Drugs

Indications