Effects of HSK3486 on Cardiac Repolarization in Health Subjects (TQT)

Summary

To assess the effects of a single IV bolus of HSK3486 single dose on cardiac repolarization (QTc interval of the electrocardiogram, and to evaluate the safety and tolerability of a single IV bolus of HSK3486 in healthy subjects

Timeline

Start

2024-04-09

Primary completion

2024-05-19

Completion

2024-11-26

Publications

• Kleiman R, Rudo T, Daley W, Hu M, Yan P, Zhou R, Hou J. Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study. Drug Des Devel Ther. 2026 Jan 14;20:565051. doi: 10.2147/DDDT.S565051. eCollection 2026.

Drugs

Indications