A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors

Summary

This study will test the safety of a drug called PF-08046031 in participants with melanoma and other solid tumors that have no current approved treatment or have spread through the body. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. The study will have 3 parts. Part A and B of the study will find out how much PF-08046031 should be given to participants. Part C will use the information from Parts A and B to see if PF-08046031 is safe and if it works to treat solid tumor cancers.

Timeline

Start

2025-05-01

Primary completion

2026-02-23

Completion

2026-02-23

Outcome

Outcome not reported

Stopped (Business): “The trial was terminated for strategic reasons. The decision was not based on any safety and/or efficacy concerns.”

Drugs

Indications