drugset / Trial / NCT06801353

A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal Polyps

NCT06801353

Phase 4 Not yet recruiting 90 enrolled Beijing Tongren Hospital
NaSingle-groupOpen-labelTreatment

Summary

Recently, several biologic therapies have become available for treating chronic rhinosinusitis with nasal polyps (CRSwNP). However, not every patient responds to these treatments. This clinical trial aims to develop a non-invasive predictive model to help determine how effective IL-4Rα targeted monoclonal antibody therapy will be for individuals with CRSwNP.

Timeline

Start
2025-02-01
Primary completion
2025-12-01
Completion
2026-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CM310 Monoclonal antibody Subcutaneous
Background Mometasone furoate Other / unclassified 200 ug Intranasal