drugset / Trial / NCT06801730

Irinotecan Liposomes Combined With Bevacizumab in the Treatment of Recurrent Glioma

NCT06801730 ↗

Phase 2 Recruiting 38 enrolled Zhifeng Tian,MD
NaSingle-groupOpen-labelTreatment

Summary

With the optimization of the dosage form of irinotecan, the replacement of ordinary irinotecan with irinotecan liposomes should improve the safety and the expected efficacy. Therefore, an exploratory study on the treatment progress of irinotecan liposomes combined with bevacizumab for recurrent brain glioma should be conducted. To evaluate the efficacy and safety of irinotecan liposomes combined with bevacizumab in the treatment of progressive/recurrent brain glioma, so as to provide more treatment options for patients with brain glioma.

Timeline

Start
2025-01-08
Primary completion
2026-12-15
Completion
2026-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 10 mg/kg —
Subject Irinotecan Small molecule 50 mg/m2 Intravenous

Indications