drugset
drugset / Trial / NCT06803199

Effects of LH and FSH on Metabolic Regulation in Cumulus Cells

NCT06803199 ↗

Recruiting 60 enrolled Kaohsiung Veterans General Hospital.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The combined use of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has improved IVF pregnancy rates in infertile women aged 35-40, but its mechanisms remain unclear. This prospective study will examine how FSH and LH combined treatment affects cumulus cell energy metabolism. Sixty participants will be divided into two groups receiving either combined therapy or FSH alone. The study will analyze patient characteristics, infertility history, and compare mitochondrial function in cumulus cells to evaluate treatment effectiveness.

Timeline

Start
2024-12-01
Primary completion
2026-12-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Luteinizing Hormone Protein / enzyme biologic — —
Background follicle-stimulating hormone Unknown — —
Comparator follicle-stimulating hormone Unknown — —

Indications

No indication recorded.