A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

Summary

The goal of this clinical trial is to learn if BGB-B455 can treat advanced or metastatic solid tumors expressing claudin 6 (CLDN6), a protein that is found on some tumors. The main questions it aims to answer are: * What is the recommended dosing for BGB-B455? * What medical problems do participants have when taking BGB-B455? The study has two parts: * Phase 1a: dose escalation and safety expansion * Phase 1b: dose expansion

Timeline

Start

2025-03-18

Primary completion

2028-04-29

Completion

2028-04-29

Drugs

Indications