drugset / Trial / NCT06808646
A Study to Assess the Effect of Ceftobiprole on the PK of Pitavastatin and on Plasma Levels of Coproporphyrin
Phase 1
Completed
12 enrolled
Basilea Pharmaceutica
Biomedical Advanced Research and Development Authority · collab
Non-randomizedSequentialOpen-labelOther
Summary
The goal of this clinical study was to determine the effect of the test drug ceftobiprole (a drug approved for the treatment of bacterial infections) on the elimination of pitavastatin (a drug approved for the treatment of increased levels of cholesterol in blood) from the body. This interaction was investigated by pharmacokinetic (PK) assessments. The clinical study also investigated the safety of ceftobiprole and how well ceftobiprole was tolerated by healthy subjects when it was administered in combination with pitavastatin.
Timeline
- Start
- 2025-01-17
- Primary completion
- 2025-02-25
- Completion
- 2025-02-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ceftobiprole | Small molecule | 500 mg | Intravenous |
| Subject | Pitavastatin | Small molecule | 2 mg | Oral |
Indications
No indication recorded.