drugset / Trial / NCT06810778

Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

NCT06810778

Phase 1/2 Recruiting 12 enrolled Jonsson Comprehensive Cancer Center
NaSequentialOpen-labelTreatment

Summary

This is an open-label, phase I/II study of duvelisib in combination with Venetoclax for patients with relapsed/refractory NHL. Duvelisib is an FDA approved, marketed product used to treat certain patients with leukemia and lymphoma and Venetoclax, which is approved for treatment of certain patients with acute myeloid leukemia. The combination of these two drugs is experimental. Experimental means that it is not approved by the United States Food and Drug Administration (FDA). The researchers want to find out how safe it is to combine these drugs and how well this combination can work for your cancer.

Timeline

Start
2025-05-02
Primary completion
2030-06-01
Completion
2031-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Duvelisib Small molecule 15 mg
Subject Duvelisib Small molecule 25 mg
Subject Venetoclax Small molecule 200 mg
Subject Venetoclax Small molecule 400 mg
Subject Venetoclax Small molecule 800 mg