drugset / Trial / NCT06814132
A Study to Evaluate the Effect of MK-5684 in Male Participants With Severe Renal Impairment (RI) and With End-stage Renal Disease (ESRD) (MK-5684-010)
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The goal of the study is to learn what happens to levels of MK-5684 in people with severe renal impairment and end-stage renal disease versus a healthy person's body over time. Researchers will compare what happens to MK-5684 after hemodialysis in people with severe renal impairment and end-stage renal disease versus healthy people.
Timeline
- Start
- 2025-04-07
- Primary completion
- 2025-10-04
- Completion
- 2025-10-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Opevesostat | Small molecule | — | Oral |
| Background | Fludrocortisone | Other / unclassified | — | Oral |
| Background | Prednisone | Other / unclassified | — | Oral |