drugset / Trial / NCT06814964

rhTNK-tPA Thrombolytic Removal of Intraventricular Hemorrhage

NCT06814964

Phase 1 Recruiting 18 enrolled Beijing Tiantan Hospital
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this pilot study is to determine the safety and optimal dose of clot lysis with rhTNK-tPA for intraventricular hemorrhage, using stereotactic guidance for extraventricular drain placement.

Timeline

Start
2025-03-01
Primary completion
2025-05-01
Completion
2025-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tenecteplase Protein / enzyme biologic 0.009 mg/ml Other
Subject Tenecteplase Protein / enzyme biologic 0.018 mg/ml Other
Subject Tenecteplase Protein / enzyme biologic 0.027 mg/ml Other