drugset / Trial / NCT06818773

Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer

NCT06818773

Phase 4 Not yet recruiting 35 enrolled Eastern Hepatobiliary Surgery Hospital
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of inetetamab in combination with chemotherapy ± immunotherapy as a first-line treatment for HER2-positive advanced biliary tract cancer, providing theoretical evidence and practical guidance for further optimizing treatment regimens and improving therapeutic outcomes.

Timeline

Start
2025-02
Primary completion
2026-12-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Inetetamab Monoclonal antibody 6 mg/kg Intravenous
Background Cisplatin Other / unclassified 25 mg/m2
Background Gemcitabine Small molecule 1000 mg/m2