drugset / Trial / NCT06819449

Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients

NCT06819449

Recruiting 50 enrolled South Valley University
RandomizedParallel-groupOpen-labelTreatment

Summary

Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.

Timeline

Start
2024-12-20
Primary completion
2025-12-10
Completion
2025-12-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clofazimine Small molecule
Comparator Dapsone Small molecule

Indications