drugset / Trial / NCT06819449
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.
Timeline
- Start
- 2024-12-20
- Primary completion
- 2025-12-10
- Completion
- 2025-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clofazimine | Small molecule | — | — |
| Comparator | Dapsone | Small molecule | — | — |