Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants

Phase 1 Completed 50 enrolled Vertex Pharmaceuticals Incorporated

Non-randomizedParallel-groupOpen-labelTreatment

The purpose of this study is to evaluate the effect of SUZ on the pharmacokinetics of oral contraceptives.

Evaluation	Drug	Modality	Dose	Route
Subject	Norgestimate	Small molecule	—	Oral
Subject	Suzetrigine	Small molecule	—	Oral
Subject	drospirenone	Unknown	—	Oral
Subject	ethinyl estradiol	Small molecule	—	Oral

No indication recorded.