drugset / Trial / NCT06825260

PEG3350 vs Senna After Urogyn Surgery

NCT06825260

Phase 4 Recruiting 254 enrolled St. Joseph's Health, New York
RandomizedParallel-groupTriple-blindTreatment

Summary

The goal of this study is to evaluate whether polyethylene glycol 3350 (PEG3350) versus senna is better at relieving postoperative constipation after urogynecologic surgery. The main questions it aims to answer are: What number of patients taking PEG3350 have obstructed defecation syndrome (ODS), a form of constipation, vs those taking senna in the week after urogynecologic surgery? What patient-level and procedure-level characteristics are associated with postoperative ODS, in patients taking PEG3350 vs senna? participants will: Take their randomized medication daily for seven days after surgery Fill out an ODS questionnaire before and one week after surgery Complete a daily bowel diary for 7 days after surgery

Timeline

Start
2025-04-23
Primary completion
2027-03
Completion
2027-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Senna Traditional medicine (herbal / TCM) 8.6 mg Oral
Comparator polyethylene glycol Other / unclassified 17 g Oral