drugset / Trial / NCT06826001

Various Procedural Treatment Options for Androgenetic Alopecia

NCT06826001

Phase 2 Not yet recruiting 190 enrolled Sheikh Zayed Medical College
RandomizedParallel-groupOpen-labelTreatment

Summary

Androgenetic alopecia (AGA)is the most common form of alopecia. It predominantly affects males, but there has been a significant surge in female preponderance too, over the last decade Minoxidil belong to the anti-hypertensive class but it also affects the potassium channels present in vascular smooth muscles and hair follicles. This potassium channel activity may stimulate the microcirculation around the hair follicles and induces arteriolar vasodilation, thereby encouraging conditions conducive to hair growth Topical administration of finasteride offers the potential to reduce systemic effects related to its mechanism of action by preferentially inhibiting 5-a reductase in the scalp, as has been suggested in recent years so in this study we are going to compare efficacy of topical minoxidil versus topical finasteride in treatment of androgenetic alopecia

Timeline

Start
2025-02
Primary completion
2025-07
Completion
2025-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Finasteride Small molecule 0.25 % Topical
Comparator Minoxidil Small molecule 5 % Topical

Indications