drugset / Trial / NCT06827665

Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation

NCT06827665 ↗

Phase 1/2 Recruiting 10 enrolled Jordan University Hospital Hanan Jafar · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

For the first time, allografts from human-extracted teeth will be prepared and evaluated in a prospective clinical trial to assess their efficacy for alveolar ridge preservation. The reconstruction and preservation of the alveolar ridge after tooth extraction are essential for future prosthetic rehabilitation. Autogenous bone grafts, while effective, are limited by donor site morbidity and insufficient graft quantity. Allogenic dentin grafts from healthy human donors present a scalable solution. This study aims to evaluate the biocompatibility and effectiveness of two types of allogenic dentin grafts-demineralized dentin allografts (DDA) and whole tooth allografts (WTA)-for alveolar ridge preservation, contributing to innovative, sustainable dental practices.

Timeline

Start
2025-01-01
Primary completion
2027-01-30
Completion
2027-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Whole tooth allografts (WTA) Other / unclassified — —
Subject demineralized dentin allografts (DDA) Other / unclassified — —

Indications

No indication recorded.