drugset / Trial / NCT06828341

A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression

NCT06828341 ↗

NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to learn if allogeneic CAR-T cells can treat patients with advanced gliomas. The main questions it aims to answer are: Evaluate the safety of allogeneic CAR-T cells in the treatment of advanced gliomas. To evaluate the effectiveness of allogeneic CAR-T cells in the treatment of advanced gliomas and to study its immunological properties in patients.

Timeline

Start
2024-06-13
Primary completion
2024-07-06
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject CAR-T Cell therapy 1e+06 cells/kg Intrathecal

Indications