The Effect of Curcumin on Inflammatory Markers in Hemodialysis Patients

Summary

The goal of this clinical trial is to learn if curcumin can lower the inflammation in participants with chronic kidney disease (CKD) undergoing hemodialysis (HD). The main questions it aims to answer are: Does curcumin lower can lower profinflamatory markers in participants with CKD on HD? Researchers will compare curcumin to a placebo (a look-alike substance that contains no drug) to see if curcumin works to help the treatment in participants with CKD on HD. Researchers will compare nutritional status and side effects after taking the supplement. Participants will: Take the curcumin or a placebo twice a day for 3 months Visit the clinic once every week for checkups and tests.

Timeline

Start

2025-03-15

Primary completion

2025-09-30

Completion

2026-12-30

Publications

• Background Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004 Sep 23;351(13):1296-305. doi: 10.1056/NEJMoa041031.
• Background Cozzolino M, Galassi A, Pivari F, Ciceri P, Conte F. The Cardiovascular Burden in End-Stage Renal Disease. Contrib Nephrol. 2017;191:44-57. doi: 10.1159/000479250. Epub 2017 Sep 14.

Drugs

Indications

No indication recorded.