drugset
drugset / Trial / NCT06832098

Nicotine Patch Plus Nicotine Mouth Spray Versus Nicotine Reduction for Vaping Cessation

NCT06832098 ↗

Phase 3 Recruiting 774 enrolled University of Auckland, New Zealand Flinders University · collabMedical University of South Carolina · collabUniversity College, London · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

This research focuses on maximizing the chances of successfully quitting vaping. A large, pragmatic community-based clinical trial is planned in New Zealand to build on existing evidence from previous vaping and smoking cessation research undertaken by the study team. The effectiveness of combination nicotine replacement therapy (NRT) compared to nicotine tapering on vaping abstinence has not yet been investigated, but both provide an opportunity to increase success with vaping cessation, especially when combined with written behavioural support to further boost quit rates. The planned trial will test whether using combination NRT will help more New Zealanders to quit vaping long-term, compared with a vape nicotine tapering plan. Participants in both groups will also receive written vaping cessation behavioural support.

Timeline

Start
2025-03-25
Primary completion
2027-04-30
Completion
2027-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Nicotine Unknown 1 mg Oral
Subject Nicotine Unknown 21 mg Other

Indications

No indication recorded.