drugset / Trial / NCT06836973

Blinatumomab for Treatment of Refractory Myasthenia Gravis

NCT06836973

Phase 2/3 Not yet recruiting 2 enrolled Da, Yuwei, M.D.
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate the efficacy and safety of Blinatumomab in the treatment of refractory myasthenia gravis, with the expectation of offering a new therapeutic option for refractory patients. The main questions it aims to answer are: * Does Blinatumomab improve patients' clinical symptoms? * Is Blinatumomab safe for the treatment of myasthenia gravis? Participants will: * Receive two cycles of intravenous Blinatumomab infusion, each lasting 5 days, with a 1-week interval between cycles. * Visit the clinic once every 4 weeks for checkups and tests. * Keep a diary of their symptoms and the types and dosages of medications.

Timeline

Start
2025-04-01
Primary completion
2028-03-31
Completion
2028-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody 9 ug Intravenous

Indications