drugset / Trial / NCT06840119
Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers
Non-randomizedSequentialOpen-labelTreatment
Summary
This phase 1/2 first-in-human study is designed to test the safety and efficacy of IMC-R117C (PIWIL1 × CD3 ImmTAC® Bispecific Protein) as a single agent and in combination with other therapies in HLA-A\*02:01-positive participants with selected advanced PIWIL1-Positive cancers.
Timeline
- Start
- 2024-01-10
- Primary completion
- 2026-11-30
- Completion
- 2027-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | IMC-R117C | Protein / enzyme biologic | — | Intravenous |