drugset / Trial / NCT06840119

Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers

NCT06840119 ↗

Phase 1/2 Recruiting 600 enrolled Immunocore Ltd
Non-randomizedSequentialOpen-labelTreatment

Summary

This phase 1/2 first-in-human study is designed to test the safety and efficacy of IMC-R117C (PIWIL1 × CD3 ImmTAC® Bispecific Protein) as a single agent and in combination with other therapies in HLA-A\*02:01-positive participants with selected advanced PIWIL1-Positive cancers.

Timeline

Start
2024-01-10
Primary completion
2026-11-30
Completion
2027-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject IMC-R117C Protein / enzyme biologic — Intravenous

Indications