drugset / Trial / NCT06841913
Woodsmoke Exposure, Influenza Infection, and Nasal Immunity
Phase 4
Recruiting
112 enrolled
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupDouble-blindBasic science
Summary
This study will investigate the effects of woodsmoke (WS) exposure on human nasal mucosal immune responses to viral infection. The study tests the hypotheses that WS exposure modifies biomarkers of nasal mucosal immune function, increases in Live Attenuated Influenza Virus (LAIV) -induced nasal symptoms, and reduces mucosal antibody production.
Timeline
- Start
- 2025-09-26
- Primary completion
- 2028-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LAIV | Vaccine | — | Intranasal |