drugset / Trial / NCT06847464
A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323.
Non-randomizedSequentialOpen-labelBasic science
Summary
The primary aim of the study is to assess the effect of itraconazole, carbamazepine, quinidine, and fluconazole individually on the pharmacokinetics and safety of EDP-323 in healthy adult participants. Each participant's duration in the study will be dependent upon which study part they are enrolled.
Timeline
- Start
- 2025-01-27
- Primary completion
- 2025-05-24
- Completion
- 2025-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EDP-323 | Unknown | — | — |
| Background | Carbamazepine | Small molecule | — | — |
| Background | Fluconazole | Small molecule | — | — |
| Background | Itraconazole | Small molecule | — | — |
| Background | Quinidine | Small molecule | — | — |