drugset / Trial / NCT06849219
Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia
RandomizedParallel-groupSingle-blindTreatment
Summary
Trigeminal neuralgia is a debilitating neurological condition, affecting quality of life in most affected patients. Carbamazepine has traditionally been used for the management of this condition, but it has a moderate effectiveness and a poor side-effect profile. Oxcarbazepine is more tolerable, and has a more favorable side-effect profile. This study aims to compare the effectiveness of oxcarbazepine and carbamazepine in the management of this condition, for improved prescription practices in the future.
Timeline
- Start
- 2024-09-21
- Primary completion
- 2025-01-30
- Completion
- 2025-03-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Carbamazepine | Small molecule | 1200 mg | — |
| Subject | Oxcarbazepine | Small molecule | 1800 mg | — |