drugset / Trial / NCT06849219

Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia

NCT06849219

Phase 4 Active not recruiting 122 enrolled Jinnah Postgraduate Medical Centre
RandomizedParallel-groupSingle-blindTreatment

Summary

Trigeminal neuralgia is a debilitating neurological condition, affecting quality of life in most affected patients. Carbamazepine has traditionally been used for the management of this condition, but it has a moderate effectiveness and a poor side-effect profile. Oxcarbazepine is more tolerable, and has a more favorable side-effect profile. This study aims to compare the effectiveness of oxcarbazepine and carbamazepine in the management of this condition, for improved prescription practices in the future.

Timeline

Start
2024-09-21
Primary completion
2025-01-30
Completion
2025-03-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carbamazepine Small molecule 1200 mg
Subject Oxcarbazepine Small molecule 1800 mg

Indications