drugset / Trial / NCT06851858

Efficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist

NCT06851858

Phase 2 Active not recruiting 69 enrolled AstraZeneca
RandomizedSequentialTriple-blindTreatment

Summary

This Phase II study is a randomized, parallel group, double blinded, placebo-controlled, multicenter to evaluate the efficacy, safety, and tolerability of AZD6234 in adults with overweight or obesity and type 2 diabetes on stable GLP-1 RA therapy.

Timeline

Start
2025-03-12
Primary completion
2026-05-27
Completion
2026-05-27

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD6234 Small activating RNA (saRNA) Subcutaneous