drugset / Trial / NCT06852365
Combined Oral Contraceptive Pill and Resistance Starch
Phase 2
Recruiting
100 enrolled
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study will enroll women with PCOS to study the effects of first line therapy, oral contraceptive pills, and then either 12 weeks of resistant starch or 12 weeks of placebo to explore if resistant starch improves cardiometabolic parameters or impacts gut dysbiosis compared to placebo.
Timeline
- Start
- 2025-06-10
- Primary completion
- 2028-04
- Completion
- 2028-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Desogestrel | Small molecule | 0.15 mg | — |
| Comparator | ethinyl estradiol | Small molecule | 20 ug | — |