drugset / Trial / NCT06853171
Safety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric Disorders
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to assess the safety, tolerability, and pharmacokinetics (PK) of multiple doses and ratios of xanomeline and trospium chloride in an IR capsule (KarXT) and dual-burst release of xanomeline with immediate-release trospium chloride in adolescents with psychiatric disorders.
Timeline
- Start
- 2025-04-29
- Primary completion
- 2025-07-22
- Completion
- 2025-07-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Trospium | Small molecule | — | — |
| Subject | Xanomeline | Small molecule | — | — |