Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke

Summary

The purpose of this study is to assess the effectiveness and safety of Qingre Huatan formula versus placebo on preventing early neurological deterioration in patients with acute ischemic stroke within 48 hours after onset.

Timeline

Start

2025-06-13

Primary completion

2026-10-24

Completion

2026-10-29

Publications

• Zheng X, Yang Z, Wu H, Zhao M, Que C, Xiong X, Mu Y, Zhang G, Kang L, Gao Y, Lai X. Efficacy and safety of Qingre Huatan Formula for the prevention of early neurological deterioration in patients with acute ischemic stroke (QUIET): rationale and design for a randomized double-blind placebo-controlled study. Front Med (Lausanne). 2026 Apr 13;13:1754648. doi: 10.3389/fmed.2026.1754648. eCollection 2026.

Drugs

Indications