drugset / Trial / NCT06858410

Lorlatinib Compared with Concurrent/ Sequential Chemoradiotherapy in Stage III ALK Positive Lung Adenocarcinoma

NCT06858410

Phase 3 Not yet recruiting 36 enrolled Guangdong Association of Clinical Trials
RandomizedParallel-groupOpen-labelTreatment

Summary

The project is a Phase III, randomized, open-label, multicenter study in which approximately 36 patients with unresectable Stage III ALK positive Lung Adenocarcinoma will be randomized 1:1 to receive lorlatinib or concurrent/sequential platinum-based chemoradiotherapy

Timeline

Start
2025-03
Primary completion
2030-03
Completion
2030-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lorlatinib Small molecule 100 mg Oral